Coronavirus is âmanifestingâ as a deadly new inflammatory syndrome in some children, a British study revealed yesterday. Â
Health Secretary Matt Hancock said last week that he was âvery worriedâ by an NHS alert over a serious autoimmune response. Â
The study into eight cases of children admitted to intensive care with coronavirus-related inflammatory syndrome found that all tested positive for virus antibodies â showing they have previously had Covid-19, often without displaying symptoms. Â
Experts said the study, published in The Lancet, supports the view that the virus is the cause.Â
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The children, aged four to 14, were all treated in intensive care at Evelina London Childrenâs Hospital in mid-April. One, a previously healthy 14-year-old boy, died of a stroke after being admitted. Â
Seven of the eight were clinically obese and six were from Bame (black, Asian and minority ethnic) backgrounds. All had âunrelenting fever, rash and generalised extremity painâ, vomiting and diarrhoea. Â
A common clinical feature was inflammation of the heart and blood vessels, which caused one child to have a âgiant coronary aneurysmâ after being discharged. Â
While all tested positive for virus antibodies, nearly all had tested negative for the active virus in swab tests while in hospital. Â
Scientists said this raised the possibility that the symptoms are part of a delayed immune response to the infection in children. Â
The study, led by consultant paediatrician Dr Shelley Riphagen, said a further 12 children with similar symptoms have since been treated. Dr Jeremy Rossman, a virologist at the University of Kent, said the findings were âvery concerningâ.Â
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